Severe sepsis is known to result in various neurological long-term deficits in human. Recently, a link between severe, lethal sepsis and significant hearing loss with correlating histomorphological inner ear changes in mice (C57BL/6) was observed. However, if similar observations can be made in severe, non-lethal sepsis in mice is unclear. This study evaluates mice after severe, non-lethal seps...

in this investigation, diabetes was induced in adult male sprague-dawley rats by single intraperitoneal injection of streptozotocin (stz) at 45 mg kg-1 of body weight. a group comprised of 8 diabetic rats was treated with metformin at 100 mg kg-1 of body weight for reducing the elevated blood glucose level. the results revealed that, in the untreated diabetic rats, the body and testicular weigh...

Methylenedioxymethamphetamine (MDMA),the Ecstasy brand, leads to cell death in many tissues such askidney because of its oxidative properties. The present study aimed to investigate the possible effects ofpentoxifylline as a vasodilators on ecstasy induced renal damage. This experimental study was carried out infour groups of six male wistar rats weighing 250-300 g (n=24). The control group was...

Aim: to assess the dynamics of histolological changes in lung under acute baclofen poisoning. Materials and methods: The study was performed on 20 male Wistar rats weighing 200-215 g aged weeks. animals were divided into four groups (5 each) – controls, group 1 (baclofen, 3h.), 2 4,5 h.) 3 24 h.). Results: thickness intraalveolar septi considerably lower than controls. hours after administratio...